About the role
Peptide Chemist:
- Plan and execute solid-phase and solution-phase peptide synthesis (SPPS/LPPS) using automated synthesizers such as Syro and CEM Liberty Blue
- Independently handle peptide synthesis across scales from gram to 1 kg, with troubleshooting abilities
- Purify and characterize peptides using preparative HPLC, analytical HPLC, LC-MS, and MS
- Operate, calibrate, and maintain lab equipment to keep synthesis workflows running smoothly
- Maintain compliance with laboratory safety and SHE (Safety, Health & Environment) standards
- Review relevant literature to inform synthetic strategy and troubleshooting approaches
- Keep accurate, timely experimental records (lab notebooks, batch records, ELN entries as applicable)
High Potent APIs (HPAPI):
- Perform hands-on laboratory chemistry activities involving high-potency APIs / potent compounds.
- Execute chemical reactions, work-ups, purification and related laboratory processes.
- Handle HPAPIs in accordance with applicable safety, containment and handling procedures.
- Maintain accurate laboratory records, experimental data and documentation.
- Support process development, optimization and troubleshooting activities.
- Perform analytical sample preparation and coordinate with analytical teams as required.
- Follow established GMP, EHS and laboratory safety requirements.
- Support investigation and resolution of laboratory/process-related issues.
- Where required, support chemistry activities related to ADC and highly potent payloads.
- Work effectively with cross-functional teams including analytical and other chemistry groups.
Organic Chemist:
- Hands-on experience in performing chemical reactions from mg to gram scale independently under scientific guidance
- Strong knowledge of analytical and purification techniques, including NMR, Mass, HPLC, CombiFlash, and column chromatography
- Skilled in handling reaction setups, glassware assemblies, reagent charging, temperature control, and nitrogen operations
- Excellent documentation and data management practices with the ability to follow scientific procedures, patents, and experimental instructions accurately
Scaleup Chemist:
- Experience in process R&D, scale-up synthesis, and purification from gm to kg scale
- Skilled in handling 50L/100L GLR assemblies and basic technology transfer activities
- Proficient in 1H NMR, HPLC, and LCMS interpretation
- Strong project execution and team collaboration skills
Antibody Drug Conjugation Chemist (ADC)
- Synthesis and purification of complex antibody drug conjugate (ADC) molecules
- Synthesis of different types of linkers – using natural and unnatural amino acids, PEGs
- Synthesis of highly potent drug molecules – payloads
- Purification of complex and large molecules by flash column and HPLC
- Handling various type chemistry with different payloads
- Interpretation and characterisation of higher molecular weight compounds
Requirements
Peptide Chemist:
- M.Sc. or M.Pharm in Organic Chemistry, Medicinal Chemistry
- 2–4 years of hands-on experience in peptide synthesis
Principal Scientist;
- PhD/MSc in Organic Chemistry / Medicinal Chemistry or related field.
- Strong experience in CRO/CDMO research environment.
- Proven team management experience with exposure to handling multiple projects.
- Excellent communication and client-facing skills.
- Ability to drive productivity, scientific excellence, and team development.
Organic Chemist:
- Master’s in Organic Chemistry with 1-3 years of experience in the CRO Industry Strong organisational, project management and problem-solving skills with impeccable multi-tasking abilities.
- Proactive, highly motivated with a "can do" attitude
- Exceptional interpersonal skills.
Peptide/Scaleup/Antibody Drug Conjugation (ADC) Chemist:
- Master’s in Organic Chemistry with a minimum of 2 years and a maximum of 6 years of experience in the CRO/API Industry
- Adherence to safe practices and procedures
- Contribution to the development of safety protocols and systems
- Must be able to prioritize and organize work responsibilities in order to meet deadlines
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